ACER3 |
---|
|
Identifiers |
---|
Aliases | ACER3, APHC, PHCA, alkaline ceramidase 3, PLDECO |
---|
External IDs | OMIM: 617036; MGI: 1913440; HomoloGene: 5410; GeneCards: ACER3; OMA:ACER3 - orthologs |
---|
Gene location (Human) |
---|
| Chr. | Chromosome 11 (human)[1] |
---|
| Band | 11q13.5 | Start | 76,860,859 bp[1] |
---|
End | 77,026,797 bp[1] |
---|
|
Gene location (Mouse) |
---|
| Chr. | Chromosome 7 (mouse)[2] |
---|
| Band | 7|7 E1 | Start | 98,206,389 bp[2] |
---|
End | 98,321,208 bp[2] |
---|
|
RNA expression pattern |
---|
Bgee | Human | Mouse (ortholog) |
---|
Top expressed in | - endothelial cell
- inferior ganglion of vagus nerve
- mucosa of ileum
- corpus callosum
- pancreatic epithelial cell
- pars reticulata
- Pars compacta
- Brodmann area 46
- subthalamic nucleus
- buccal mucosa cell
|
| Top expressed in | - conjunctival fornix
- cornea
- interventricular septum
- hair follicle
- skin of external ear
- sciatic nerve
- decidua
- skin of back
- lobe of prostate
- skin of abdomen
|
| More reference expression data |
|
---|
BioGPS | |
---|
|
Gene ontology |
---|
Molecular function | - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
- hydrolase activity
- phytoceramidase activity
- N-acylsphingosine amidohydrolase activity
- dihydroceramidase activity
- ceramidase activity
- calcium ion binding
- zinc ion binding
- metal ion binding
| Cellular component | - integral component of membrane
- integral component of Golgi membrane
- integral component of endoplasmic reticulum membrane
- Golgi membrane
- Golgi apparatus
- endoplasmic reticulum membrane
- endoplasmic reticulum
- membrane
| Biological process | - sphingosine biosynthetic process
- sphingolipid biosynthetic process
- phytosphingosine biosynthetic process
- ceramide metabolic process
- positive regulation of cell population proliferation
- inflammatory response
- myelination
- regulation of programmed cell death
- ceramide catabolic process
- lipid metabolism
- sphingolipid metabolic process
| Sources:Amigo / QuickGO |
|
Orthologs |
---|
Species | Human | Mouse |
---|
Entrez | | |
---|
Ensembl | | |
---|
UniProt | | |
---|
RefSeq (mRNA) | |
---|
NM_001300953 NM_001300954 NM_001300955 NM_018367 |
| |
---|
RefSeq (protein) | |
---|
NP_001287882 NP_001287883 NP_001287884 NP_060837 |
| |
---|
NP_079684 NP_001347544 NP_001347545 NP_001347546 |
|
---|
Location (UCSC) | Chr 11: 76.86 – 77.03 Mb | Chr 7: 98.21 – 98.32 Mb |
---|
PubMed search | [3] | [4] |
---|
|
Wikidata |
View/Edit Human | View/Edit Mouse |
|