Elastosis perforans serpiginosa

Medical condition

Elastosis perforans serpiginosa
Other names	EPS^[1]

Elastosis perforans serpiginosa: Hyperkeratotic plaque of papules^[2]
Specialty	Dermatology

Elastosis perforans serpiginosa is a unique perforating disorder characterized by transepidermal elimination of elastic fibers and distinctive clinical lesions, which are serpiginous in distribution and can be associated with specific diseases.^[3]^[4]

Histopathology of elastosis perforans serpiginosa: Degenerated elastic fibers and transepidermal perforating canals (arrow points at one of them)^[2]
This condition is inherited in an autosomal dominant manner.

References

^ "OMIM Entry - 130100 - ELASTOSIS PERFORANS SERPIGINOSA; EPS". omim.org. Retrieved 19 April 2019.
^ ^a ^b Hosen, Mohammad J.; Lamoen, Anouck; De Paepe, Anne; Vanakker, Olivier M. (2012). "Histopathology of Pseudoxanthoma Elasticum and Related Disorders: Histological Hallmarks and Diagnostic Clues". Scientifica. 2012: 1–15. doi:10.6064/2012/598262. ISSN 2090-908X. PMC 3820553. PMID 24278718.
-Creative Commons Attribution 3.0 Unported license
^ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). Page 1041. McGraw-Hill. ISBN 0-07-138076-0.
^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.

External links

Classification	D ICD-10: L87.2 (ILDS L87.200) OMIM: 130100 MeSH: C536202 DiseasesDB: 29813
External resources	eMedicine: article/1074280

Cutaneous keratosis, ulcer, atrophy, and necrobiosis

Epidermal thickening

keratoderma: Keratoderma climactericum
Paraneoplastic keratoderma
- Acrokeratosis paraneoplastica of Bazex
Aquagenic keratoderma
Drug-induced keratoderma
psoriasis
- Keratoderma blennorrhagicum

Necrobiosis/granuloma

Necrobiotic/palisading	Granuloma annulare Perforating Generalized Subcutaneous Granuloma annulare in HIV disease Localized granuloma annulare Patch-type granuloma annulare Necrobiosis lipoidica Annular elastolytic giant-cell granuloma Granuloma multiforme Necrobiotic xanthogranuloma Palisaded neutrophilic and granulomatous dermatitis Rheumatoid nodulosis Interstitial granulomatous dermatitis/Interstitial granulomatous drug reaction
Foreign body granuloma	Beryllium granuloma Mercury granuloma Silica granuloma Silicone granuloma Zirconium granuloma Soot tattoo Tattoo Carbon stain
Other/ungrouped	eosinophilic dermatosis Granuloma faciale

Dermis/
localized CTD

Cutaneous lupus erythematosus	chronic: Discoid Panniculitis subacute: Neonatal ungrouped: Chilblain Lupus erythematosus–lichen planus overlap syndrome Tumid Verrucous Rowell's syndrome
Scleroderma/ Morphea	Localized scleroderma Localized morphea Morphea–lichen sclerosus et atrophicus overlap Generalized morphea Atrophoderma of Pasini and Pierini Pansclerotic morphea Morphea profunda Linear scleroderma
Atrophic/ atrophoderma	Lichen sclerosus Anetoderma Schweninger–Buzzi anetoderma Jadassohn–Pellizzari anetoderma Atrophoderma of Pasini and Pierini Acrodermatitis chronica atrophicans Semicircular lipoatrophy Follicular atrophoderma Linear atrophoderma of Moulin Atrophia maculosa varioliformis cutis
Perforating	Kyrle disease Reactive perforating collagenosis Elastosis perforans serpiginosa Perforating folliculitis Acquired perforating dermatosis
Skin ulcer	Pyoderma gangrenosum
Other	Calcinosis cutis Sclerodactyly Poikiloderma vasculare atrophicans Ainhum/Pseudo-ainhum