Glycobiarsol

Glycobiarsol
Structural formula of glycobiarsol
Space-filling model of the glycobiarsol molecule
Names
Preferred IUPAC name
Oxobismuthanyl hydrogen [4-(2-hydroxyacetamido)phenyl]arsonate
Other names
[4-[(2-Hydroxyacetyl)amino]phenyl]-oxobismuthanyl-oxyarsinic acid
Identifiers
CAS Number
  • 116-49-4 checkY
3D model (JSmol)
  • Interactive image
ChemSpider
  • 10669861 checkY
ECHA InfoCard 100.003.767 Edit this at Wikidata
EC Number
  • 204-143-1
KEGG
  • D07358
PubChem CID
  • 16682839
UNII
  • E3U8347QWJ checkY
CompTox Dashboard (EPA)
  • DTXSID1048754 Edit this at Wikidata
InChI
  • InChI=1S/C8H10AsNO5.Bi.O/c11-5-8(12)10-7-3-1-6(2-4-7)9(13,14)15;;/h1-4,11H,5H2,(H,10,12)(H2,13,14,15);;/q;+1;/p-1 checkY
    Key: FATAHBJTOKXSDH-UHFFFAOYSA-M checkY
  • OCC(=O)NC1=CC=C(C=C1)[As](O)(=O)O[Bi]=O
Properties
Chemical formula
 C8H9AsBiNO6
Molar mass 499.063 g·mol−1
Pharmacology
P01AR03 (WHO) QP51AD03 (WHO) QP51AD53 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Chemical compound

Glycobiarsol (trade name Milibis) is an organometallic antiprotozoal agent that has been used in humans[1] as well as in dogs.[2]

References

  1. ^ Berberian, D. A. (1954). "The trichomonacidal activity of milibis (glycobiarsol)". New York State Journal of Medicine. 54 (22): 3102–3105. PMID 13214428.
  2. ^ Kibble, R. M. (1969). "Glycobiarsol for the control of Trichuris vulpis infection in the dog". Australian Veterinary Journal. 45 (8): 387. doi:10.1111/j.1751-0813.1969.tb06633.x. PMID 5389346.
  • v
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Antiparasitics – antiprotozoal agents – agents against amoebozoa/amebicide (P01)
Entamoeba
Tissue amebicides
Nitroimidazole derivatives
Other
Luminal amebicides
Hydroxyquinoline derivatives
Dichloroacetamide derivatives
Aminoglycoside
Other/ungrouped
Acanthamoeba


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