PRO-LAD
- DE: NpSG (Industrial and scientific use only)
- UK: Under Psychoactive Substances Act
- US: Analogue to a Schedule I/II drug but only if it is intended for human consumption
- Illegal in France[1]
- (8β)-N,N-Diethyl-6-propyl-9,10-didehydroergoline-8-carboxamide
- 65527-63-1 Y
- 44457803
- 21106361 Y
- RVR83W9XMC
- ChEMBL22258 Y
- DTXSID50215824
- Interactive image
- CCN(CC)C(=O)[C@@H]2C=C1c3cccc4[nH]cc(C[C@H]1N(C2)CCC)c34
- InChI=1S/C22H29N3O/c1-4-10-25-14-16(22(26)24(5-2)6-3)11-18-17-8-7-9-19-21(17)15(13-23-19)12-20(18)25/h7-9,11,13,16,20,23H,4-6,10,12,14H2,1-3H3/t16-,20-/m1/s1 Y
- Key:HZKYLVLOBYNKKM-OXQOHEQNSA-N Y
PRO-LAD is an analogue of LSD. It is described by Alexander Shulgin in the book TiHKAL. PRO-LAD is a psychedelic drug similar to LSD, and is around as potent as LSD itself with an active dose reported at between 100 and 200 micrograms.[2]
Legal status
On June 10, 2014 the UK Advisory Council on the Misuse of Drugs (ACMD) recommended that PRO-LAD be specifically named in the UK Misuse of Drugs Act as a class A drug despite not identifying it as ever having been sold or any harm associated with its use.[3] The UK Home office accepted this advice and announced a ban of the substance to be enacted on 6 January 2015 as part of The Misuse of Drugs Act 1971 (Amendment) (No. 2) Order 2014.
PRO-LAD is illegal in Switzerland as of December 2015.[4]
See also
- LSD (METH-LAD)
- AL-LAD
- ALD-52
- ETH-LAD
- FLUORETH-LAD
References
- ^ "Arrêté du 20 mai 2021 modifiant l'arrêté du 22 février 1990 fixant la liste des substances classées comme stupéfiants" [Order of May 20, 2021 amending the order of February 22, 1990 setting the list of substances classified as narcotics]. www.legifrance.gouv.fr (in French). 20 May 2021.
- ^ Hoffman AJ, Nichols DE (September 1985). "Synthesis and LSD-like discriminative stimulus properties in a series of N(6)-alkyl norlysergic acid N,N-diethylamide derivatives". Journal of Medicinal Chemistry. 28 (9): 1252–1255. doi:10.1021/jm00147a022. PMID 4032428.
- ^ ACMD (10 June 2014). "Update of the Generic Definition for Tryptamines" (PDF). UK Home Office. p. 12. Retrieved 10 June 2014.
- ^ "Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien" [Ordinance of the EDI on the lists of narcotics, psychotropic substances, precursor substances and auxiliary chemicals]. Der Bundesrat [The Federal Council] (in German).
Further reading
- Hoffman AJ, Nichols DE (September 1985). "Synthesis and LSD-like discriminative stimulus properties in a series of N(6)-alkyl norlysergic acid N,N-diethylamide derivatives". Journal of Medicinal Chemistry. 28 (9): 1252–1255. doi:10.1021/jm00147a022. PMID 4032428.
- Niwaguchi T, Nakahara Y, Ishii H (May 1976). "[Studies on lysergic acid diethylamide and related compounds. IV. Syntheses of various amide derivatives of norlysergic acid and related compounds]". Yakugaku Zasshi. 96 (5): 673–678. doi:10.1248/yakushi1947.96.5_673. PMID 987200.
- Pfaff RC, Huang X, Marona-Lewicka D, Oberlender R, Nichols DE (1994). "Lysergamides Revisited.". NIDA Research Monograph 146: Hallucinogens: An Update (PDF). United States Department of Health and Human Services. p. 52. Archived from the original (PDF) on 2015-07-23.
External links
- PRO-LAD entry in TIHKAL
- PRO-LAD entry in TiHKAL • info
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