EIF1B

Protein-coding gene in the species Homo sapiens
EIF1B
Identifiers
AliasesEIF1B, GC20, eukaryotic translation initiation factor 1B
External IDsMGI: 1916219; HomoloGene: 22219; GeneCards: EIF1B; OMA:EIF1B - orthologs
Gene location (Human)
Chromosome 3 (human)
Chr.Chromosome 3 (human)[1]
Chromosome 3 (human)
Genomic location for EIF1B
Genomic location for EIF1B
Band3p22.1Start40,309,707 bp[1]
End40,312,424 bp[1]
Gene location (Mouse)
Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)[2]
Chromosome 9 (mouse)
Genomic location for EIF1B
Genomic location for EIF1B
Band9|9 F4Start120,321,298 bp[2]
End120,324,396 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right ventricle

  • left ventricle

  • pons

  • myocardium

  • myocardium of left ventricle

  • right auricle

  • endothelial cell

  • Pars compacta

  • apex of heart

  • lateral nuclear group of thalamus
Top expressed in
  • ventricular zone

  • spermatocyte

  • facial motor nucleus

  • medial ganglionic eminence

  • anterior horn of spinal cord

  • neural tube

  • primary oocyte

  • seminiferous tubule

  • CA3 field

  • motor neuron
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • translation initiation factor activity
  • RNA binding
  • ribosomal small subunit binding
Cellular component
  • cellular component
  • eukaryotic 43S preinitiation complex
Biological process
  • translational initiation
  • protein biosynthesis
  • regulation of translational initiation
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

10289

68969

Ensembl

ENSG00000114784

ENSMUSG00000006941

UniProt

O60739

Q9CXU9

RefSeq (mRNA)

NM_005875

NM_026892

RefSeq (protein)

NP_005866

NP_081168

Location (UCSC)Chr 3: 40.31 – 40.31 MbChr 9: 120.32 – 120.32 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Eukaryotic translation initiation factor 1b is a protein that in humans is encoded by the EIF1B gene.[5][6]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000114784 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000006941 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Fields C, Adams MD (Feb 1994). "Expressed sequence tags identify a human isolog of the suil translation initiation factor". Biochem Biophys Res Commun. 198 (1): 288–91. doi:10.1006/bbrc.1994.1040. PMID 7904817.
  6. ^ "Entrez Gene: EIF1B eukaryotic translation initiation factor 1B".

Further reading

  • Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Hu RM, Han ZG, Song HD, et al. (2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 97 (17): 9543–8. Bibcode:2000PNAS...97.9543H. doi:10.1073/pnas.160270997. PMC 16901. PMID 10931946.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

External links

  • v
  • t
  • e
  • 2if1: HUMAN TRANSLATION INITIATION FACTOR EIF1, NMR, 29 STRUCTURES
    2if1: HUMAN TRANSLATION INITIATION FACTOR EIF1, NMR, 29 STRUCTURES
  • v
  • t
  • e
Proteins
Initiation factor
Bacterial
Mitochondrial
Archaeal
  • aIF1
  • aIF2
  • aIF5
  • aIF6
Eukaryotic
eIF1
eIF2
eIF3
eIF4
eIF5
eIF6
Elongation factor
Bacterial/​Mitochondrial
Archaeal/​Eukaryotic
Release factor
Ribosomal Proteins
Cytoplasmic
60S subunit
40S subunit
Mitochondrial
39S subunit
28S subunit
Other concepts


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