OR10R2

Protein-coding gene in the species Homo sapiens
OR10R2
Identifiers
AliasesOR10R2, OR1-8, OR10R2Q, olfactory receptor family 10 subfamily R member 2
External IDsHomoloGene: 121586; GeneCards: OR10R2; OMA:OR10R2 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for OR10R2
Genomic location for OR10R2
Band1q23.1Start158,472,220 bp[1]
End158,480,936 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • organ system

  • thyroid gland

  • blood

  • multicellular organism
    n/a
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • G protein-coupled receptor activity
  • olfactory receptor activity
  • transmembrane signaling receptor activity
  • signal transducer activity
Cellular component
  • integral component of membrane
  • plasma membrane
  • membrane
Biological process
  • sensory perception of smell
  • detection of chemical stimulus involved in sensory perception of smell
  • detection of chemical stimulus involved in sensory perception
  • signal transduction
  • response to stimulus
  • G protein-coupled receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

343406

n/a

Ensembl

ENSG00000198965

n/a

UniProt

Q8NGX6

n/a

RefSeq (mRNA)

NM_001004472
NM_001395749

n/a

RefSeq (protein)

NP_001004472

n/a

Location (UCSC)Chr 1: 158.47 – 158.48 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Olfactory receptor 10R2 is a protein that in humans is encoded by the OR10R2 gene.[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000198965 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ a b "Entrez Gene: OR10R2 olfactory receptor, family 10, subfamily R, member 2".

Further reading

  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes" (PDF). Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
Family 2
Family 3
Family 4
Family 5
Family 6
Family 7
Family 8
Family 9
Family 10
Family 11
Family 12
Family 13


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