OR5AT1

Protein-coding gene in the species Homo sapiens
OR14A16
Identifiers
AliasesOR14A16, OR5AT1, olfactory receptor family 14 subfamily A member 16
External IDsHomoloGene: 128064; GeneCards: OR14A16; OMA:OR14A16 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for OR14A16
Genomic location for OR14A16
Band1q44Start247,814,660 bp[1]
End247,824,119 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • testicle

  • right testis

  • left testis
    n/a
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • G protein-coupled receptor activity
  • odorant binding
  • olfactory receptor activity
  • signal transducer activity
Cellular component
  • integral component of membrane
  • plasma membrane
  • membrane
Biological process
  • sensory perception of smell
  • signal transduction
  • response to stimulus
  • detection of chemical stimulus involved in sensory perception of smell
  • G protein-coupled receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

284532

n/a

Ensembl

ENSG00000196772

n/a

UniProt

Q8NHC5

n/a

RefSeq (mRNA)

NM_001001966

n/a

RefSeq (protein)

NP_001001966

n/a

Location (UCSC)Chr 1: 247.81 – 247.82 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Olfactory receptor 14A16 is a protein that in humans is encoded by the OR14A16 gene.[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000196772 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ a b "Entrez Gene: OR5AT1 olfactory receptor, family 5, subfamily AT, member 1".

Further reading

  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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Class I
(fish-like receptors)
Family 51
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Family 56
Class II
(tetrapod specific receptors)
Family 1
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